Antibody-dependent cellular cytotoxicity (ADCC)

NK cells also express FcγRIII (CD16). Antibody-coated cells can be recognized by NK cells, and such cells can then be lysed (Chapter 33). This process is referred to as antibody-dependent cellular cytotoxicity (ADCC).

CD16分为两种(CD16a、CD16b),其中CD16a表达于NK细胞表面,这也提示了中性粒细胞和巨噬细胞也有参与ADCC的能力。

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